Problem
Experts agree that worldwide investments in mental health research are meagre, and historically, this clinical area has sought phased and marketable advances. In an article published in 2006, Tom Insel, then Director of the National Institute of Mental Health, wrote that 鈥淚n contrast to researchers in cancer and heart disease who have sought cures and preventions, biological psychiatrists in both academia and industry have set their sights on incremental advances, such as drugs with fewer adverse effects.鈥� He听proposed that the field of psychiatry will need to develop groundbreaking strategies for prevention of mental disorders.
Solution
To that end, Dr. Christopher Lowry鈥檚 team at CU Boulder has been working on developing novel therapies for prevention of stress-related psychiatric disorders. Specifically, Dr. Lowry鈥檚 team has developed a new nutritional fitness approach to enhance stress resilience and prevent stress-related psychiatric disorders including anxiety disorders, affective disorders听and PTSD. This approach consists of exposures to certain mycobacteria (the 鈥済ood bacteria鈥�), a genus of common and abundant environmental bacteria with immunoregulatory and anti- inflammatory properties. This research group has published multiple peer-reviewed papers on this technology听and are the leading researchers in the science of using mycobacteria to enhance stress resilience. Ten novel strains of mycobacteria have been discovered so far and technical progress continues here at CU.
Market Application
Applications for the technology include听clinical psychiatry and psychology.
What's Next?
The spin-off company, Mycobacterium Therapeutics, Inc., is engaging in strategic talks with several industry partners and is currently looking for business and technical executives to join the team and/or fill board seats. 听
Dipika Singh: 听dipika.singh@colorado.edu