Ìý

**The 2018 deadline for this opportunity has passed or the internal application slot has been granted. Updated information will be posted when the next funding cycle opens.**

Ìý

Program SummaryÌý

The National Institute on Alcohol Abuse and Alcoholism invites cooperative agreement applications to evaluate the cumulative and progressive effects of combined HIV infection and alcohol abuse in patient populations that are growing older and living well longer. This project must address several questions of current interest, including, but not limited to coinfection with the Hepatitis C virus, involvement of peripheral neuropathy in frailty, potential neurotoxic effects of antiretroviral medications, and interactive effects with advancing age on sensory and motor functioning.Ìý Clinical research knowledge that would be gained from this project could position "translational" efforts in the development of better and more focused treatments for observed comorbid neurological, cognitive, and motor deficits, which may also be relevant to other disease-affected aging populations.Ìý This project must directly address the NIH Office of AIDS Research priority for understanding "HIV-associated comorbidities, coinfections, and complications including:Ìý addressing the impact of HIV-associated comorbidities, including tuberculosis, malignancies; cardiovascular, neurological, and metabolic complications; and premature aging associated with long-term HIV disease and antiretroviral therapy."

Clinical trials not allowed.

Deadlines

Internal Competition Deadline: 11:59pm MST May 21, 2018

Letter of Intent Deadline: 3:00pm MST June 3, 2018

Application Deadline: 3:00pm MST July 3, 2018

Internal Application Requirements (all in PDF format)

  • Up to 2-page project summary
  • Up to 2-page curriculum vitae
  • Up to 1-page budget overview: a basic budget outlining project costs is sufficient; detailed OCG budgets are not required.

To access the online application, visit:

Eligibility

Only grantees previously funded under RFA-AA-12-011 are eligible to apply.

Limited Submission Guidelines

The applicant institution may submit only one application under this announcement.

Award Information and Duration

Funding Amount: $1,250,000; award budget must not exceed $800,000 in direct costs per year.

Number of Awards: 1

Project Period: Maximum project period is 5 years.